Tag Archives: Health

How far away are we from 3D printed drugs and medical devices?

pharma-3d-printed-drugs.pngDecades ago, we used to say technology was the wave of the future.  Today, with technologies such as additive manufacturing, we are living in the future.

Additive manufacturing, or 3D printing, is being used increasingly across numerous industries, from automotive to entertainment to pharmaceutical and medical device.

According to a recent report, North America is expected to account for the largest share of the global 3D printing medical device market in 2017, a global market which is projected to reach USD 1.88 billion by 2022 from USD 0.84 billion in 2017.

While 3D printing is here, the future holds many questions. As the use of 3D printing continues to expand in the pharmaceutical and medical device space, how the FDA regulatory regime and traditional products liability principles will evolve are among these questions.

Read more

Tagged , ,

Managing safety in AM facilities

This is a good white paper from UL on one of the main wider implications of 3D printing.  


The UL AM white paper, “Managing Safety in Additive Manufacturing Facilities,” is now available. In speaking with Norm Lowe, UL’s manager of AM facility safety services, the white paper is in response to the rapidly increasing demand to better understand AM safety considerations. “There so much growth within the industry that manufacturers need to understand the safety factors associated with AM, just as they would with any other manufacturing process. But unlike traditional manufacturing, that knowledge hasn’t been readily available,” states Lowe.

Though the white paper discusses safety issues in additive manufacturing, it specifically focuses on safety issues associated with metal AM. Lowe added, “The paper identifies the principle sources of risk associated with additive manufacturing, and then presents a methodology for establishing a safety management system or modifying an existing system in advance of the introduction of additive manufacturing capabilities. We also included recommendations on the development of safety assessments for additive manufacturing operations.”

Download Managing Safety in Additive Manufacturing Facilities now.  

Tagged

The next pharmaceutical revolution could be 3D bioprinted

Body organs such as kidneys, livers and hearts are incredibly complex tissues. Each is made up of many different cell types, plus other components that give the organs their structure and allow them to function as we need them to.

For 3D printed organs to work, they must mimic what happens naturally – both in terms of arrangement and serving a biological need. For example, a kidney must process and excrete waste in the form of urine.

Read more

Tagged ,

How 3D printing is transforming biomedical research and healthcare

3d-printing-healthcareOrgans-on-chip for drug testing, 3D-printed pills delivering personalised dosages of medication, low cost prosthetics and more

Yesterday the Dubai Health Authority announced that doctors had saved the life of a sixty-year-old Omani woman who suffered from a cerebral aneurysm, with assistance from a state-of-the-art custom 3D-printed model of the patient’s brain dilated arteries to help plan the complex surgery.

The patient was admitted to the hospital after suffering from severe bleeding in the brain. Due to the complexity and rarity of the patient’s case the doctors needed a 3D model that would allow them to understand exactly how to reach the arteries in a safe manner. Without the 3D model the surgery would have taken longer and the risk would have been higher.

Read more

Tagged ,

Testing a soft artificial heart

It looks like a real heart. And this is the goal of the first entirely soft artificial heart: to mimic its natural model as closely as possible. The silicone heart has been developed by Nicholas Cohrs, a doctoral student in the group led by Wendelin Stark, Professor of Functional Materials Engineering at ETH Zurich. The reasoning why nature should be used as a model is clear. Currently used blood pumps have many disadvantages: their mechanical parts are susceptible to complications while the patient lacks a physiological pulse, which is assumed to have some consequences for the patient. “Therefore, our goal is to develop an artificial heart that is roughly the same size as the patient’s own one and which imitates the human heart as closely as possible in form and function,” says Cohrs.

A well-functioning artificial heart is a real necessity: about 26 million people worldwide suffer from heart failure while there is a shortage of donor hearts. Artificial blood pumps help to bridge the waiting time until a patient receives a donor heart or their own heart recovers.

Read more (including video)

Tagged ,

The additive manufacture ancillary problem

There is a problem surrounding the additive manufacturing (AM) and 3D printing (3DP) industry that is rarely discussed, but is not going away any time soon.

I would be the last person to dispute the amazing capabilities of AM and 3DP hardware systems used for industrial applications. The ability to build complex parts in one piece and the advantages this brings of increased strength, lighter weight, reduced material consumption and assembly component consolidation for an increasing range of applications are all well documented.

The focus tends to be on the hardware, but this does not convey the full picture of what is required to get that part ‘off the machine’.

Read more

Tagged

UL assessed the safety of 3D printing

In the first phase of its project to generate standards for safer 3D printing, the UL assess airborne particles and volatile compounds released during extrusion of several polymer filaments.

two-year study from Underwriters Laboratoryexamines the implications of ultrafine particles and volatile organic compounds released during 3D printing on human health. Although enclosures and other features on 3D printers are usually included to minimize the release of airborne particles during extrusion, further investigation is needed to develop standards that will ensure the safety of people in the area.

UL presented its results at the Summit on the Safety Science of 3D Printing. Its study explores several polymer filaments, including ABS and PLA, which produce similar levels of ultrafine particles. They identified 50 volatile organic compounds (VOCs) released during printing, of which the most significant were styrene, caprolactam, and lactide.

Read more

Tagged

Five of the biggest challenges facing manufacturers in 3D printing

While 3D printing is undoubted entering mainstream manufacture – and at rates that are faster than many realise – it is important to note that there continue to be challenges to be overcome.  This isn’t a surprise, after all all disruptive technologies do.  This article from Apple Rubber discusses some of the key ones.


3d printing challengesAccording to Wohlers Associates, the global 3D printing market is expected to reach $21 billion by 2020 — quadrupling its size in just four years. While 3D printing, also referred to as additive manufacturing, comes with many benefits, such as freedom of design, easy prototyping, customization and streamlined logistics, it also poses many challenges.

In order to fully leverage this transformational technology, we identified five 3D printing challenges that manufacturing leaders must understand.

Read More

Tagged , , ,

The health effects of 3D printing

Basic steps you can take to protect your patrons and staff

3D printing closeupAs makerspaces and fab labs increase in popularity, more and more libraries are adding 3D-printing capabilities. According to a 2015 American Library Association (ALA) report, 428 public library branches have made this technology available. Some potential issues of 3D printing, such as the threat of printing weapons and copyrighted works, are often considered. However, discussion of the health hazards associated with 3D printing is rare.

Ultrafine particles and volatile organic compounds
Several studies have shown that 3D printers produce high amounts of ultrafine particles (UFPs) and volatile organic compounds (VOCs) while in use, and that these particles and vapors are detectable for many hours after the printers have been shut off. UFPs have been linked to adverse health conditions, such as asthma and cardiovascular issues, because they can pass through the lungs and travel to other organs. They can also transfer toxic material into the body, including blood and tissue cells. The US Environmental Protection Administration has classified many VOCs as toxic air pollutants. Exposure to certain VOCs, such as benzene and methylene chloride, has been linked to cancer.

Read more

Tagged , ,